Manchester City will be crowned Premier League champions if they beat Chelsea at Etihad Stadium on Saturday.
The teams will also meet in the Champions League final later this month, though Pep Guardiola says his sole focus is securing the title.
“There is not one thought about the final of the Champions League because we don’t have the Premier League in our hands,” said the City boss.
“I’m so cautious. I think if you don’t have it, you don’t talk about it.”
City’s victory against Paris Saint-Germain on Tuesday sent them through to their first Champions League final and gives Guardiola the chance to lift the trophy for the third time as a manager after his double success with Barcelona in 2009 and 2011.
However, the Spaniard says winning the domestic league is always his priority over European success, with City on the brink of a third Premier League title in four seasons under his stewardship.
“Always I’ve said the Premier League is the most important title,” he added.
“Financially for the club, qualification for the Champions League is the most important title, maybe, but there is no doubt what is the most important thing.
“Of course the Champions League is so special, it’s nice, but this one means consistency and many things.”
Manchester City’s hopes of an unprecedented quadruple were ended by Chelsea last month with a 1-0 defeat in the FA Cup semi-final at Wembley.
Blues boss Thomas Tuchel says that game and Saturday’s meeting will have no bearing on the Champions League final.
“I think the final in Istanbul will be pretty unique no matter the score tomorrow, no matter if we win, they win or if we draw,” he said.